Diet-Microbiome Interactions and the Risk of Pouchitis in Ileal Pouch-Anal Anastomosis
نویسندگان
چکیده
منابع مشابه
Characterization of the Gut-Associated Microbiome in Inflammatory Pouch Complications Following Ileal Pouch-Anal Anastomosis
INTRODUCTION Inflammatory complications following ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC) are common and thought to arise through mechanisms similar to de novo onset inflammatory bowel disease. The aim of this study was to determine whether specific organisms in the tissue-associated microbiota are associated with inflammatory pouch complications. METHODS Patients havi...
متن کاملLactobacillus acidophilus alleviates pouchitis after ileal pouch-anal anastomosis in rats
AIM To assess the therapeutic potential of Lactobacillus acidophilus (LA) for the treatment of pouchitis in a rat model. METHODS Sprague Dawley rats underwent proctocolectomy and ileal pouch-anal anastomosis followed by administration of dextran sulfate sodium (DSS) to induce pouchitis. Rats with pouchitis were randomly divided into three groups: no intervention (NI), normal saline (NS, 3 mL/...
متن کاملThe diameter of the ileal J-pouch-anal anastomosis as an important risk factor of pouchitis – clinical observations
BACKGROUND Patients' quality of life after restorative proctocolectomy depends on the potential complications. Stricture of the ileal pouch-anal anastomosis is one of the complications following restorative proctocolectomy. MATERIAL/METHODS We analyzed the correlation between the diameter of the anastomosis and clinical parameters, including pouchitis disease activity index (PDAI), the activi...
متن کاملClinical and physiological aspects of ileal pouch-anal anastomosis.
Proctocolectomy with ileal pouch-anal anastomosis is the surgical treatment of choice for severe chronic ulcerative colitis and familial polyposis coli because the entire colonic mucosa is removed while anal function can be preserved and the necessity for permanent ileostomy is eliminated. Long-term functional results are generally gratifying, as defecation frequency and degree of incontinence ...
متن کاملLaparoscopic proctocolectomy with ileal j-pouch anal anastomosis in children.
BACKGROUND/AIMS We aimed to evaluate postoperative fecal incontinence scales of children who underwent laparoscopic proctocolectomy and ileal J-pouch anastomosis for familial adenomateous polyposis (FAP) and inflammatory bowel disease (IBD). MATERIALS AND METHODS Fecal incontinence scores were collected at 3 months post-surgery. A retrospective chart review was also performed to obtain the de...
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ژورنال
عنوان ژورنال: Journal of Crohn's and Colitis
سال: 2019
ISSN: 1873-9946,1876-4479
DOI: 10.1093/ecco-jcc/jjz136